New insights into blood flow fluctuations offer hope in fight against cardiovascular disease

Proposed mechanisms of and contributors to Piezo1-mediated shear-induced NETosis. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-51211-1 Researchers have uncovered how fluctuations in blood flow that occur when there is a narrowing in the arteries contribute to harmful inflammation and blood clot formation, revealing the critical role that blood flow–driven forces play in the development and progression of cardiovascular diseases. These new insights from researchers at the Baker Heart and Diabetes Institute, published today (August 22) in Nature Communications, have led to the identification of a target that could mitigate harmful inflammation and blood clot formation, and potentially have a significant impact Read More