New approach for better efficacy of immunotherapies

Single-cell RNA- and TCR sequencing reveal favored V?1+ usage with expanded CDR3 identity patterns in ?? T cells of MSS CRC. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-51025-1 The most common form of colorectal cancer, microsatellite-stable colorectal cancer (MSS CRC), can currently only be treated to a limited extent with modern immunotherapies. A research team led by MedUni Vienna has now identified the possible cause of treatment failure and thus found a way to improve treatment for patients. The study was recently published in Nature Communications. The researchers, led by Victoria Stary (Department of General Surgery, Comprehensive Cancer Center of MedUni Read More