Key discovery advances fight to reduce breast cancer recurrence

Loss of G?13 in ER+ breast cancer cells leads to increased cell growth and tumour development, suggesting that G?13 may suppress tumours in this subtype of cancer. Credit: Liao Pei-Ju, Duke-NUS Medical School In looking for new ways to fight breast cancer, scientists from Duke-NUS Medical School have unmasked a surprising role of a protein generally associated with cancer growth. They have discovered that in estrogen receptor-positive (ER+) breast cancer, this protein acts as a tumor suppressor instead. ER+ breast cancer constitutes about 80% of all breast cancer diagnoses, yet nearly 50% of women diagnosed with it experience a relapse Read More