Mechanisms of postoperative pain reveal a path for localized and targeted therapy

Pain neurons in the skin (magenta) and mast cells (yellow) with a subset of pain neurons (substance P+neurons, cyan). Credit: MedUni Vienna/Rohit Jain & Shweta Tikoo An international research group led by MedUni Vienna and IMBA—Institute of Molecular Biotechnology, Vienna, has made significant progress in understanding the mechanisms that influence the sensation of pain after surgery. Currently available treatment methods for post-operative pain can cause considerable side effects and are often only partially effective. The latest findings reveal a new possibility for localized and targeted therapy. The study has now been published in Science Immunology. In their research, the team Read More