Scientist discover rare genotype causing early menopause

Credit: Nadezhda Moryak from Pexels Scientists have identified a sequence variant in the CCDC201 gene that, when inherited from both parents homozygous, causes menopause on average nine years earlier. deCODE genetics and collaborators from Iceland, Denmark, the UK, and Norway published a study in Nature Genetics today revealing a rare genotype with a significant impact on women’s health. Age at menopause significantly affects fertility and disease risk. This research focused on recessive models, or on individuals with two copies of a sequence variant called homozygotes, which are less commonly studied than the additive model, which mainly relies on individuals carrying Read More