Researchers identify immune profile for lung disease caused by allergic reaction

Fibrotic hypersensitivity pneumonitis is a chronic and progressive interstitial lung disease, caused by an immune response to inhaled foreign antigens or allergens. Researchers from Yale’s Section of Pulmonary, Critical Care and Sleep Medicine have used single-cell sequencing technology to provide the first high-resolution atlas of this disease, revealing a previously unrecognized immune signature. Their findings were published in the American Journal of Respiratory and Critical Care Medicine. Fibrotic hypersensitivity pneumonitis belongs to a category of diseases known as pulmonary fibrosis, which is characterized by inflammation and irreversible scarring in the lungs. Other diseases under this umbrella include idiopathic pulmonary fibrosis, Read More