Scientists develop potential stealth cancer therapy

Credit: ACS Central Science (2024). DOI: 10.1021/acscentsci.4c00559 Sneaking by cancer’s defenses, by disguising tumor-fighting antibodies inside the molecules cancer uses to nourish tumor growth, is the basis of a novel therapy from Yale Cancer Center researchers at the Yale School of Medicine (YSM). As explained in a paper published July 15 in ACS Central Science, the Trojan-horse therapy proved effective against several cancer tumor types in the laboratory, including brain tumors that can be difficult to reach with therapy due to the protective blood-brain barrier. The successes can be attributed to therapy-carrying antibodies that have been strategically redesigned from lupus Read More