Tissue homeostasis: plasmacytoid dendritic cells monitor bone marrow, initiating on-demand megakaryocyte formation. Uniform distribution of megakaryocytes (green) controlled by plasmacytoid dendritic cells (magenta) within a human bone marrow section. Credit: Hellen Ishikawa-Ankerhold Platelets play an essential role in wound healing. Underproduction can cause devastating bleeding, while overproduction increases the deadly risk of thromboses. Maintaining a constant level of platelets in the blood (homeostasis) is therefore vitally important. Platelets are continuously formed by megakaryocytes (MKs) and released into the blood. Researchers at LMU University Hospital and the Biomedical Center Munich (BMC) have now made a groundbreaking discovery: innate immune system cells Read More
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