Roles of PEDF in exercise-induced suppression of senescence and its impact on lung pathology in mice

Credit: Aging (2024). DOI: 10.18632/aging.205976 A new research paper titled “Roles of pigment epithelium-derived factor in exercise-induced suppression of senescence and its impact on lung pathology in mice” has been published in Aging. Senescent cells contribute to tissue aging and underlie the pathology of chronic diseases. The benefits of eliminating senescent cells have been demonstrated in several disease models, and the efficacy of senolytic drugs is currently being tested in humans. Exercise training has been shown to reduce cellular senescence in several tissues; however, the mechanisms responsible remain unclear. In this new study, researchers Hiromichi Tsushima, Hirobumi Tada, Azusa Asai, Read More