Wednesday, January 22, 2025

Novel protein detects and responds to changes in blood flow

Model for junctional endothelial shear stress mechanotransduction. Credit: The EMBO Journal (2024). DOI: 10.1038/s44318-024-00142-0 When blood moves through your body, it exerts a frictional force on the walls of blood vessels. This force, known as fluid shear stress, has important effects on vascular development, function, and disease. A team at Yale, led by Martin Schwartz, Ph.D., Robert W. Berliner Professor of Medicine (cardiology), has identified a protein that helps your body sense and respond to changes in this shear stress. The study, “Latrophilin-2 mediates fluid shear stress mechanotransduction at endothelial junctions,” is published in The EMBO Journal. This protein, latrophilin-2, Read More

No comments:

Post a Comment