T cells can manipulate the memory of innate immune cells, researchers show

Graphical Abstract. Credit: Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2024.114664, https://www.cell.com/cell-reports/fulltext/S2211-1247(24)01015-5 Research from Radboud university medical center reveals that T cells from the adaptive immune system can manipulate the memory of innate immune cells. Previously, it was believed that the memory of innate immune cells operated independently. This surprising connection opens up new possibilities for the treatment of various diseases. A mouse model shows that no immunosuppressive drugs are needed after an organ transplantation if this interaction between T cells and the innate immunity is temporarily blocked after the transplantation. The article was published in Cell Reports. The adaptive immune system Read More