Finding new treatments for genetic tumor-predisposition syndrome

Clinically diverse cNFs give rise to organoids with similar histopathological features. Credit: Cell Reports Methods (2024). DOI: 10.1016/j.crmeth.2024.100772 A new report describes a promising approach to studying neurofibromatosis type 1 (NF1), a genetic condition with limited treatment options. The condition causes a number of different cancerous and non-cancerous tumors to form throughout the body. Among these tumors are cutaneous neurofibromas, benign tumors that grow from nerve terminals in the skin. Current treatment to reduce tumor growth in patients is limited to surgery, which can lead to scarring, re-growth of the tumor and may not be feasible at all when these benign Read More