Discovery of how blood clots harm brain and body in COVID-19 points to new therapy

Fibrin (red) and toxic microglia (green) in the brain of a mouse infected with COVID-19. Credit: Jae Kyu Ryu and Katerina Akassoglou of Gladstone Institutes In a study that reshapes what we know about COVID-19 and its most perplexing symptoms, scientists have discovered that the blood coagulation protein fibrin causes the unusual clotting and inflammation that have become hallmarks of the disease, while also suppressing the body’s ability to clear the virus. Importantly, the team also identified a new antibody therapy to combat all of these deleterious effects. Published in Nature, the study by Gladstone Institutes and collaborators overturns the Read More