A new screening method for measuring blood-brain barrier permeability

SwRI developed a new screening method (on the right) that uses in vitro brain cells to identify potential drug formulations, depicted in blue and green, that can penetrate the brain’s complex and highly selective blood-brain barrier with hydrodynamic forces to simulate movement or a heartbeat. Credit: Southwest Research Institute Scientists at Southwest Research Institute have developed a new screening method to identify drug formulations that can penetrate the blood-brain barrier (BBB), to facilitate treatment of brain diseases and conditions. “The BBB protects the brain and central nervous system from potentially harmful substances in the bloodstream, regulating the transport of essential Read More