Study suggests targeting oligodendrocytes could help reduce amyloid beta production

Scientist captures images of human oligodendrocytes in a dish (stained green), which produce the protein implicated in causing Alzheimer’s disease. Credit: Francesca Lam (CC-BY 4.0, creativecommons.org/licenses/by/4.0/) Oligodendrocytes are an important source of amyloid beta (A?) and play a key role in promoting neuronal dysfunction in Alzheimer’s disease (AD), according to a study published July 23, 2024 in the open-access journal PLOS Biology by Rikesh Rajani and Marc Aurel Busche from the UK Dementia Research Institute at University College London, and colleagues. AD is a devastating neurodegenerative disorder affecting millions of people worldwide. Accumulation of A?—peptides consisting of 36 to 43 Read More