Potential epigenetic modifiers targeting the alteration of methylation in colorectal cancer

by Xia & He Publishing Inc. Some epigenetic alterations detected in CRC. Credit: Gene Expression (2024). DOI: 10.14218/GE.2023.00039S Colorectal cancer (CRC) remains a significant global health concern, being the third most diagnosed cancer and the second leading cause of cancer-related deaths worldwide. In 2020 alone, CRC accounted for 1.9 million new cases and nearly 935,000 deaths. The incidence of CRC is expected to rise, with projections estimating 3.2 million new cases annually by 2040. This trend underscores the urgent need for more effective therapeutic strategies. CRC predominantly affects older adults, with around 80% of new cases occurring in individuals over Read More