by Xia & He Publishing Inc. The interaction between TAL-1 and its associated miRNAs follows a unidirectional pattern, in which miRNAs that target TAL-1 are downregulated, resulting in elevated TAL-1 levels. Credit: Gene Expression (2024). DOI: 10.14218/GE.2023.00076 T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive form of leukemia that arises from the malignant transformation of T-cell progenitors. This disease is most commonly diagnosed in children, where it accounts for a significant portion of pediatric leukemia cases, but it also affects adults. The clinical presentation of T-ALL includes symptoms resulting from bone marrow failure, such as anemia, thrombocytopenia, and neutropenia, as Read More
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