‘Mini lungs’ research leads to multiple COVID-19 discoveries

hiPSC-derived LOs are susceptible to infection with multiple strains of SARS-CoV-2, validated in primary human lung epithelia. Credit: Proceedings of the National Academy of Sciences (2024). DOI: 10.1073/pnas.2408109121 Scientists at Sanford Burnham Prebys, University of California San Diego and their international collaborators have reported that more types of lung cells can be infected by SARS-CoV-2 than previously thought, including those without known viral receptors. The research team also reported for the first time that the lung is capable of independently mustering an inflammatory antiviral response without help from the immune system when exposed to SARS-CoV-2. This work is especially timely, Read More