Link between type 2 diabetes mellitus and spinal degenerative disorder may be method-dependent

The association between type 2 diabetes mellitus (T2DM) and spinal degenerative disorders (SDDs) may be method-dependent, according to a study published online July 3 in The Journal of Bone & Joint Surgery. Ming-Xiang Zou, M.D., Ph.D., from the University of South China in Hengyang, and colleagues examined and compared the association between T2DM and SDD using observational studies and Mendelian randomization (MR) analyses. Data for the observational analyses included 44,972 participants with T2DM and 403,095 without T2DM in cross-sectional studies; 38,234 participants with SDD and 409,833 participants without SDD in case-control studies; and 35,550 participants with T2DM and 392,046 without Read More