New mechanism of immune evasion in squamous cell carcinoma offers potential for improved treatment

Reciprocal inhibition between TP63 and STAT1 regulates anti-tumor immune response through interferon-? signaling in squamous cancer. Credit: Chinese Academy of Sciences with ChatGPT A research group has revealed the tumor-extrinsic function of master regulator transcription factor-TP63 in promoting immune evasion and affecting immunotherapy efficacy in squamous cancer. Their results were published in Nature Communications. The study was led by Dr. Jiang Yanyi from Hefei Institutes of Physical Science of the Chinese Academy of Sciences, along with Dr. Lin Dechen’s team at the University of Southern California, U.S. Immunotherapy such as Read More