Graphical abstract. Credit: Li et al. In a study published in Cell Host & Microbe, a research team has demonstrated the causal link between microbial factors and dysfunction of intestinal stem cells (ISCs) in colitis. On the basis of this mechanism, they proposed a possible approach to restore ISC function in colitis. Inflammatory bowel disease (IBD) is a chronic disease characterized by microbial dysbiosis and dysfunction of ISCs in the gut. However, how these two factors are directly communicated remains poorly understood. In this study, researchers first revealed that ?2A-adrenergic Read More
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