Tuesday, July 16, 2024

Improving models to study the human heart

Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2024.114160 Northwestern Medicine scientists have developed a new method to measure and optimize the maturation process of cultured heart muscle cells, an approach that has the potential to set the future standard for a common cell model in scientific research, according to details published in Cell Reports. Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are cultured heart muscle cell models widely used to study a variety of human heart disease and responses to experimental drugs. However, newly cultured cardiomyocytes don’t accurately reflect mature heart muscle Read More

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