Single-cell genomics reveals cell type–specific and laminar changes in ASD. Credit: Science (2024). DOI: 10.1126/science.adh2602 A study led by UCLA Health has unveiled the most detailed view of the complex biological mechanisms underlying autism, showing the first link between genetic risk of the disorder to observed cellular and genetic activity across different layers of the brain. The study, titled “Molecular cascades and cell type–specific signatures in ASD revealed by single-cell genomics,” is part of the second package of studies from the National Institutes of Health consortium, PsychENCODE. Launched in 2015, Read More
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