Pioneering single-cell kidney atlas sheds light on potential treatments

Comprehensive integrated multimodal human kidney single-cell atlas. a, Overview of the multimodal analysis. b, UMAP of 338,565 cells/nuclei in an integrated human kidney snRNA-seq/scRNA-seq and snATAC–seq data generated in this study. c, UMAP of 588,425 integrated human kidney snRNA-seq/scRNA-seq and snATAC–seq data from the present study and KPMP. Credit: Nature Genetics (2024). DOI: 10.1038/s41588-024-01802-x Researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania revealed the most extensive single cell atlas of the human kidney, capturing the complexity of healthy and diseased kidneys at an unprecedented level and predicting chronic kidney disease Read More