Monday, January 27, 2025

Mitochondria support immune response to central nervous system injuries, scientists discover

Confocal images of corpus callosum with staining for Nuclei (DAPI, Blue), myelin (anti-PLP, Green) and microglia (anti-RFP, Red) taken from untreated, 10 week cuprizone and 6 week recovery RISP-cHET and RISP-cKO mice. Credit: Navdeep Chandel, PhD. Northwestern University Northwestern Medicine scientists have discovered that mitochondria are not necessary for the proliferation of specialized immune cells in the central nervous system, but do help those cells respond to demyelinating injuries, according to a study published in Nature Metabolism. “Microglia we know are connected to many neurological diseases, including decline in cognition during normal aging and Alzheimer’s Disease. People think that mitochondria Read More

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