Monday, January 27, 2025

Organoids mimicking celiac disease show new link between gluten and intestinal damage

A microscopic image of an intestinal organoid in which the nuclei of the cells are blue, epithelial cells are white, T cells are green and other immune cells are red. Credit: Antonio Santos Small, laboratory-grown balls of cells made from the intestinal tissue of people with celiac disease have revealed a previously unknown molecular link between gluten exposure and intestinal damage, according to a study by researchers at Stanford Medicine. The molecule, called IL-7, has been implicated in other autoimmune diseases including rheumatoid arthritis and multiple sclerosis, but it has never been linked to celiac disease. The study is the Read More

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