Researchers from Japan investigated how ASOs administered locally into the brains of mice models for Parkinson’s disease can help prevent the formation and spread of harmful aSyn aggregates through different regions. Their findings show ASOs could be a promoting therapeutic strategy to both prevent and control the progression of various neurodegenerative diseases. Credit: Department of Neurology and Neurological Science, TMDU Parkinson’s disease (PD), as well as many other neurodegenerative disorders, has shown a link between the abnormal aggregation of a protein called ?-synuclein (aSyn) and neuronal death. These aggregates, known as Lewy bodies and Lewy neurites depending on their subcellular Read More
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