Experimental drug shows promise in clearing HIV from brain

Phosphorylation activation of CSF1R is increased with simian immunodeficiency virus. Credit: Brain (2024). DOI: 10.1093/brain/awae153 An experimental drug originally developed to treat cancer may help clear HIV from infected cells in the brain, according to a new Tulane University study. For the first time, researchers at Tulane National Primate Research Center found that a cancer drug significantly reduced levels of SIV, the nonhuman primate equivalent of HIV, in the brain by targeting and depleting certain immune cells that harbor the virus. Published in the journal Brain, this discovery marks a significant step toward eliminating HIV from hard-to-reach reservoirs where the Read More