Scientists identify ‘unconventional’ new pathway for TB vaccines

Graphical abstract. Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2024.114426 An “unconventional” immune response now identified by scientists from the Hackensack Meridian Center for Discovery and Innovation (CDI) is a potential new pathway for developing new vaccines for tuberculosis (TB), according to a new publication. Marginal zone B (MZB) cells are a natural response to TB infection which has been long overlooked—and which might be a welcome new target that could be bolstered through new vaccines to better combat and prevent the disease, according to the new publication in the journal Cell Reports. “Our results indicate that B cells skew their immune Read More