A treatment for metastasis? Using ferroptosis to attack migrating cancer cells

Zeb1 regulates the expression of enzymes crucial for adjusting the PUFA:MUFA ratio in phospholipids. Credit: Nature Cell Biology (2024). DOI: 10.1038/s41556-024-01464-1 A treatment for metastatic cancer—researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), the University of Innsbruck, the Massachusetts Institute of Technology (MIT) and Universität Würzburg have now come a major step closer to this ambitious goal. Their approach for attacking the migrating cancer cells is to use ferroptosis—a cell death mechanism only discovered in 2012. Current experiments with laboratory substances are very promising, but further research and clinical studies are required before medicines on this basis can be used. The findings have Read More