T cells can mediate remarkable tumor regressions including complete cure in patients with metastatic cancer. Genetic alterations in an individual’s cancer cells (the mutanome) encode unique peptides (m-peptides) that can be targets for T cells. The recent advances in next-generation…
Source: Mining the mutanome: developing highly personalized Immunotherapies based on mutational analysis of tumors
Sunday, July 28, 2013
Mining the mutanome: developing highly personalized Immunotherapies based on mutational analysis of tumors
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