Constitutional trisomy 8 mosaicism as a model for epigenetic studies of aneuploidy

To investigate epigenetic patterns associated with aneuploidy we used constitutional trisomy 8 mosaicism (CT8M) as a model, enabling analyses of single cell clones, harboring either trisomy or disomy 8, from the same patient; this circumvents any bias introduced by using cells from…

Source: Constitutional trisomy 8 mosaicism as a model for epigenetic studies of aneuploidy