Mutations accumulate as a result of DNA damage and imperfect DNA repair machinery. In higher eukaryotes the accumulation and spread of mutations is limited in two primary ways: through p53-mediated programmed cell death and cellular senescence mediated by telomeres. Telomeres shorten at every…
Source:Stress induced telomere shortening: longer life with less mutations?
Saturday, March 1, 2014
Stress induced telomere shortening: longer life with less mutations?
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