Thursday, August 29, 2013

Identification of a novel infection-enhancing epitope on dengue prM using a dengue cross-reacting monoclonal antibody

Dengue virus (DENV) infection is the most important arthropod- borne viral disease in human, but antiviral therapy and approved vaccines remain unavailable due to antibody-dependent enhancement (ADE) phenomenon. Many studies showed that pre-membrane (prM)-specific antibodies do not efficiently…

Identification of a novel infection-enhancing epitope on dengue prM using a dengue cross-reacting monoclonal antibody




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