Saturday, November 1, 2014

PLD3 is accumulated on neuritic plaques in Alzheimer?s disease brains

IntroductionRecently, a whole-exome sequencing (WES) study showed that a rare variant rs145999145 composed of p.Val232Met located in exon 7 of the phospholipase D3 (PLD3) gene confers a doubled risk for late-onset Alzheimer’s disease (AD). Knockdown of PLD3 elevates the levels of…

PLD3 is accumulated on neuritic plaques in Alzheimer?s disease brains




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