Imidazoline I3 receptors (I-3R) can regulate insulin secretion in pancreatic beta-cells. It has been indicated that allantoin ameliorates hyperglycemia by activating imidazoline I2 receptors (I-2R).
Thus, the effect of allantoin on I-3R is identified in the present study.
Methods:
We used…
Allantoin activates imidazoline I-3 receptors to enhance insulin secretion in pancreatic beta-cells
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