Cell-targeting technology can isolate neuronal subpopulations and link them to behavioral states

ConVERGD-based expression requires the presence of both Cre and Flp recombinases. a, Schematic of ConVERGD. b, Schematic of ribozyme-mediated cleavage and degradation of transcribed mRNA. c, Representative images showing hSyn-ConVERGD-eGFP (green) expression in DAPI (blue)-counterstained N2a cell transfections. d, Dot plots of hSyn-ConVERGD-eGFP N2a cell transfections quantified by FACS analysis. e, Histogram compiling FACS dot plots in d. Credit: Nature Neuroscience (2024). DOI: 10.1038/s41593-024-01659-7 As gene sequencing technologies become more powerful, our understanding of cellular diversity has grown in parallel. This led scientists at St. Jude Children’s Research Hospital to Read More