Wednesday, April 2, 2014

Protoss: a holistic approach to predict tautomers and protonation states in protein-ligand complexes

The calculation of hydrogen positions is a common preprocessing step when working with crystal structures of protein-ligand complexes. An explicit description of hydrogen atoms is generally needed in order to analyze the binding mode of particular ligands or to calculate the associated binding…

Protoss: a holistic approach to predict tautomers and protonation states in protein-ligand complexes




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