Sunday, January 26, 2014

Shortening guide RNA markedly improves specificity of CRISPR-Cas nucleases

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Contact: Sue McGreeveysmcgreevey@partners.org

617-724-2764Massachusetts General Hospital


A simple adjustment to a powerful gene-editing tool may be able to improve its specificity. In a report receiving advance online publication in Nature Biotechnology, Massachusetts…

Shortening guide RNA markedly improves specificity of CRISPR-Cas nucleases




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